The gameplay is roughly the same as in Mega Man: The Power Battle, as it keeps the controls, stages and weapon-copying. There are however several new additions. The playable characters are Mega Man, Proto Man, Bass and Duo, with Duo being a new addition to the cast. The four characters feature different attributes and abilities. When playing 2-Player, only one of the players can get the Robot Master's weapon.
As in The Power Battle there are three "stories" to choose from after; finding Dr. Wily, saving Roll, and recovering the stolen parts. All stories have different Robot Masters to fight, and halfway through it the player is given a different power-up. Unlike the previous game, The Power Fighters lets the player choose freely between Robot Master stages, and is given some hints on what the Robot Masters weaknesses are. Each of the characters can perform a special attack, which is executed by releasing a full buster charge while holding the joystick up. Megaman's special move, the "Mega Upper," is simply a jumping uppercut (like the Shoryuken); Protoman's special move, the "Proto Strike," allows him to shoot a massive, short-ranged burst of energy; Bass' special move, the "Crescent Kick," (Which is like the Flash Kick, another Street Fighter ability), lets him perform a somersaulting kick; Duo's special move, the "Giant Knuckle," is a standing uppercut that flings the enemy upwards (if the attack button is pressed again after the uppercut, Duo will jump up and slam the enemy down to the ground).
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As in The Power Battle there are three "stories" to choose from after; finding Dr. Wily, saving Roll, and recovering the stolen parts. All stories have different Robot Masters to fight, and halfway through it the player is given a different power-up. Unlike the previous game, The Power Fighters lets the player choose freely between Robot Master stages, and is given some hints on what the Robot Masters weaknesses are. Each of the characters can perform a special attack, which is executed by releasing a full buster charge while holding the joystick up. Megaman's special move, the "Mega Upper," is simply a jumping uppercut (like the Shoryuken); Protoman's special move, the "Proto Strike," allows him to shoot a massive, short-ranged burst of energy; Bass' special move, the "Crescent Kick," (Which is like the Flash Kick, another Street Fighter ability), lets him perform a somersaulting kick; Duo's special move, the "Giant Knuckle," is a standing uppercut that flings the enemy upwards (if the attack button is pressed again after the uppercut, Duo will jump up and slam the enemy down to the ground).
轮我童年时期怎么都是玩了些净是二代目、最终作的稀罕游戏&跟小伙伴们一起开黑。反倒是FC洛克人我在家都没好好玩，（因为没有2P手柄、第二个插孔还被我弄坏了，所以一个人玩尤其是小孩就显得~没意思，尤其是2008年左右互联网开始普及的网吧时代，不过我没去）。只能在办公室电脑上跟大家相约一起团聚了，现在就算我一个人打也显得很~捉急、无力。【小的时候一直以为洛克人有动画，结果居然只有个MV，而且后来还是YYUT万恶之源的雅颂曲子，意外的闭环了】
力量对决比较适合和基友玩（现在压根没人玩这个吧。。。），打起来难度偏低。
在模拟器上玩的，虽然是FTG只有BOSS战但是意外地蛮好玩的。
fans向，做的还凑合，属性相克的特性依然存在，打法讨巧但相对单一。